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Pre-Menstrual Syndrome Medications & Breastfeeding

Following is a list of active ingredients for various PMS medications:

	Acetaminophen	Caffeine	Ibuprofen	Pamabrom	Pyrilamine maleate
	AAP- Approved*	AAP-Approved*	AAP-Approved*
Midol Menstrual Complete	500 mg	60 mg	-	-	15 mg
Midol Pre-Menstrual Syndrome	500 mg	-	-	25 mg	15 mg
Midol Cramp & Body Aches	-	-	200 mg	-	-
Midol Teen Formula	500 mg	-	-	25 mg	-
Pamprin Multi-Symptom	500 mg	-	-	25 mg	15 mg
Premsyn PMS	500 mg	-	-	25 mg	15 mg
* Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001. Sources: midol.com (12/22/03) drugstore.com (12/22/03)

Acetaminophen and ibuprofen (pain relievers) and caffeine (a stimulant) are all approved by the AAP for use in breastfeeding mothers.

The other two drugs - pamabrom and pyrilamine maleate - are diuretics.

I have been unable to locate specific information regarding pyrilamine with regards to breastfeeding, but this medication is an antihistamine used directly in pediatrics (in some pediatric cold medications).

Pamabrom is a very mild diuretic - many pharmacists and lactation professionals consider small amounts of this drug to be safe for nursing mothers.

Page last modified: 03/03/2005
Written: 12/22/03

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